Abstract:This article evaluated comprehensively the suitability of human settlements in the heavy disaster of Wenchuan earthquake that selected main factors（disasters danger of earthquake, secondary mountain hazards, using land resources, available water resources, environmental capacity, ecosystem fragility, ecological significance, economic development level, population density, traffic dominance ），applied the technology of geographic information system and adopted the evaluation method of key factors combined with weight factors，and established the model of evaluation（ ）.The results show that: The suitable regions and more suitable regions allocated in the eastern plain and hilly areas；The moderate suitable regions located in low mountain, hilly areas, western plateau and the transition region of Longmenshan piedmont; The regions which are not suitable and worse suitable located in the alpine-gorge area. According to the results of human settlements, the industrial layout, urban spatial distribution and population scale are discussed in the article.